Interesting question.
Personally I have never used an ESD and in all the electronics and computer work I have done, it has never been an issue as far as I can tell. The one time I did see anything happen in terms of discharge into an IC (an FM receiver chip) I initially thought I had fried it but it actually worked just fine! Disclaimer: I have never done any work on a DMD board so am unaware of any issues particular to one.
I have always grounded myself on the computer case before working on computer internals.
You are far more likely to kill a chip with excessive heat than ESD - hence socket all ICs if possible rather than solder directly to a board.
