Autocad works for the line work and is a bit easier than Illustrator.
Once the line work is done the rest can be easily done in Illustrator

Illustrators pathfinder option makes lines a breeze.  I use to use cad+illustrator in some of my early work ... but after 10 years of Illustrator and a good Illustrator bible .. I eventually wrapped my fat head around it :)  Cad does make line work easy as well though.